Home ยป Does CBD REALLY work for epilepsy and seizures?

The application of CBD and medical cannabis for epilepsy is one of the most exciting developments in the last 50 years of medicine.

The current popularity of CBD for epilepsy can be attributed to the 3 part “WEED” special report by Sanjay Gupta. You can watch all three parts here: https://tinyurl.com/mx7om9b

While CBD is not a cure for epilepsy, it has shown to be a non-psychoactive, anticonvulsant agent for reducing seizures and allowing patients to decrease their anti-epileptic drugs. By decreasing their doses of anti-epileptic drugs, patients can liberate themselves from the nasty side effects often brought on by these drugs.

CBD is thought to stop seizures in 4 main ways:

1. CBD increases levels of our endocannabinoids by interfering with their degradation. The increased level of endocannabinoids helps our endocannabinoid system perform its function of maintaining balance in the body.

2. CBD reduces the excitability of neurons by modulating the flow of ions like calcium and potassium. Endocannabinoids are neuro-modulators and in this way, CBD mimics their activity.

3. CBD suppresses glutamate activity. Glutamate causes neuronal excitation.

4. CBD is a potent anti-inflammatory agent. CBD reduces inflammation of the brain (neuroinflammation). Brain inflammation is thought to make seizures worse.

People with epilepsy should only add CBD to their medication regimen under the supervision of a doctor as CBD can interact with their existing medications.

It’s important to keep in mind that CBD is not a cure-all for epilepsy. There are some children who do not respond well to CBD treatment and it does not work for everybody. Side effects, although usually not a problem with CBD, are possible. Due to the severity of epilepsy, CBD should only be used under medical supervision, especially if CBD is being used on a child with epilepsy.

Please let me know if you have any questions or comments in the comments section below.

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  • Hello,
    I am writing for a loved one. In reading your trial about using CBD yourselves for epilepsy it seems as though you only used CBD, with absolutely no THC (not even the .03). So I’m wondering, with the information about Charlotte’s Webb, why you didn’t try the small amount of THC? (CW Advanced for instance). I thought that the combination of both was key. Also, I have heard it could take months in order to build up and get the correct dosing for seizure freedom.
    Love to hear your thoughts.
    Thank you for your time.

    • Hey Tricia. Thanks for writing in and nice to hear from you. If you are referring to some of the blog posts by Alex, our in-house writer who uses CBD for his epilepsy, he does indeed use a product with a small amount of THC. He lives in Canada so he gets his CBD oil under the supervision of a doctor — something I recommend everyone do if they can, especially with epilepsy. In regard to CBD building up over time in the system, this is something I’ve also heard but it would be better confirmed with a trained medical professional as I don’t know too many details about this particular quality of CBD. But I am familiar with the idea. Thanks again for your insightful comment.