Home » CBD Oil For PTSD – CBD School Podcast #6

The use of CBD for anxiety has been studied for over two decades now. And this application of CBD for anxiety extends to the use of CBD for PTSD.

PTSD is a pathological anxiety condition caused by experiencing a past traumatic event. Common events that can cause PTSD include war, violence, and sexual abuse. Though there are countless reasons why someone might experience PTSD.

CBD and other cannabinoids like THC in medical marijuana have shown to be effective at reducing symptoms of people suffering from PTSD. CBD products may be able to be used as alternatives for people with PTSD who were unsuccessful with traditional Rx medications like antidepressants.

While the evidence for the effectiveness of CBD for anxiety and CBD for PTSD is promising, it’s important to be conscious of the fact that cannabis products may not be right for everyone and their situation. Future data from people, doctors, and researchers will help us to better understand the application of CBD for PTSD.

There is a ton of research out there for you to dive into on CBD for Post Traumatic Stress Disorder and Anxiety:

Cannabidiol, a Cannabis sativa constituent, as an anxiolytic drug: https://www.ncbi.nlm.nih.gov/pubmed/22729452

Effectiveness of Cannabidiol Oil for Pediatric Anxiety and Insomnia as Part of Posttraumatic Stress Disorder: A Case Report: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101100/

Cannabidiol as a Potential Treatment for Anxiety Disorders: https://www.ncbi.nlm.nih.gov/pubmed/26341731

Cannabidiol blocks long-lasting behavioral consequences of predator threat stress: possible involvement of 5HT1A receptors: https://www.ncbi.nlm.nih.gov/pubmed/22979992

Cannabidiol disrupts the consolidation of specific and generalized fear memories via dorsal hippocampus CB1 and CB2 receptors: https://www.ncbi.nlm.nih.gov/pubmed/28754373

Bidirectional Effects of Cannabidiol on Contextual Fear Memory Extinction: https://www.frontiersin.org/articles/10.3389/fphar.2016.00493/full

Cannabidiol Modulates Fear Memory Formation Through Interactions with Serotonergic Transmission in the Mesolimbic System: https://www.ncbi.nlm.nih.gov/pubmed/27296152

The Use of Medicinal Marijuana for Posttraumatic Stress Disorder: A Review of the Current Literature: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578915/

Modulation of fear memory by dietary polyunsaturated fatty acids via cannabinoid receptors: https://www.ncbi.nlm.nih.gov/pubmed/24518289

Enhancing cannabinoid neurotransmission augments the extinction of conditioned fear: https://www.ncbi.nlm.nih.gov/pubmed/15637635

Reductions in circulating endocannabinoid levels in individuals with post-traumatic stress disorder following exposure to the World Trade Center attacks: https://www.ncbi.nlm.nih.gov/pubmed/24035186


A current overview of cannabinoids and glucocorticoids in facilitating extinction of aversive memories: potential extinction enhancers: https://www.ncbi.nlm.nih.gov/pubmed/22687521

The endocannabinoid system and extinction learning: https://www.ncbi.nlm.nih.gov/pubmed/17952654

Cannabinoid modulation of fear extinction brain circuits: a novel target to advance anxiety treatment: https://www.ncbi.nlm.nih.gov/pubmed/23829364

Mitigation of post-traumatic stress symptoms by Cannabis resin: a review of the clinical and neurobiological evidence: https://www.ncbi.nlm.nih.gov/pubmed/22736575

Stress switches cannabinoid type-1 (CB1) receptor-dependent plasticity from LTD to LTP in the bed nucleus of the stria terminalis: https://www.ncbi.nlm.nih.gov/pubmed/24336729

Non-Antidepressant Long-term Treatment in Post-Traumatic Stress Disorder (PTSD): https://www.ncbi.nlm.nih.gov/pubmed/?term=traumatic+and+Kerbage+H

Cannabinoids and traumatic stress modulation of contextual fear extinction and GR expression in the amygdala-hippocampal-prefrontal circuit: https://www.ncbi.nlm.nih.gov/pubmed/23433741

Thanks to Martin Lee and the team at Project CBD for doing such a great job at compiling a lot of these studies I referenced: https://www.projectcbd.org/

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